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RETRACTED ARTICLE: Effect of Doxofylline on Reducing the Inflammatory Response in Mechanically Ventilated Rats with Chronic Obstructive Pulmonary Disease

Authors Liu CY, Wu JH, Chen ZY, Zhang Y, Huang CL, Lin AM, Xu XT, Gao XH

Received 16 April 2021

Accepted for publication 2 August 2021

Published 16 August 2021 Volume 2021:16 Pages 2375—2383

DOI https://doi.org/10.2147/COPD.S315639

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Richard Russell



This paper has been retracted.

Liu CY, Wu JH, Chen ZY, et al. Int J Chron Obstruct Pulmon Dis. 2021;16:2375–2383.

The Editor and Publisher of International Journal of Chronic Obstructive Pulmonary Disease are retracting the published article. Concerns were raised that the western blot results in Figure 6 had been duplicated with those from Figure 4 in Chen Z, Zhang Y, Wu J, Gao X, Huang C, Lin Y, Xu X, Li Y. The Mechanism of Penehyclidine Hydrochloride and Its Effect on the Inflammatory Response of Lung Tissue in Rats with Chronic Obstructive Pulmonary Disease During Mechanical Ventilation. Int J Chron Obstruct Pulmon Dis. 2021;16:877–885, https://doi.org/10.2147/COPD.S295329. Both sets of western blots are describing results from different studies.

In addition, the image from Figure 2N was found to have been duplicated with the same image from Figure 1N from Chen Zy, Lin Ym, Wu Jh, et al. Effect of doxofylline on pulmonary inflammatory response and oxidative stress during mechanical ventilation in rats with COPD. BMC Pulm Med 22, 66 (2022), https://doi.org/10.1186/s12890-022-01859-6.

The authors did not respond to our queries and as the findings could not be verified the Editor and Publisher made the decision to retract the article. The authors were notified of this decision.

We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

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