Back to User profile » Dr Sai-Hong Ignatius Ou
Papers published by Dr Sai-Hong Ignatius Ou:
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Time To Response In Patients With Advanced Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small-Cell Lung Cancer (NSCLC) Receiving Alectinib In The Phase II NP28673 And NP28761 Studies
Gadgeel S, Shaw AT, Barlesi F, Crino L, Yang JCH, Dingemans AM, Kim DW, de Marinis F, Schulz M, Liu S, Gupta R, Smoljanovic V, Ou SHI
Lung Cancer: Targets and Therapy 2019, 10:125-130
Published Date: 13 November 2019
![Noteworthy comment: There are several problems arising from TKIs resistance mechanisms in patients with EGFR-mutant squamous cell carcinoma of the lung. This case report adds to evidence that dual therapy (Osimertinib and Crizotinib) should be useful to EGFR-mutant lung cancers with emergent MET amplification as acquired resistance. This is a very well written case, which would be of interest to many specialties, with a clear discussion and relevant references.](assets/img/article_icons/noteworthy.png)
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Differential response to a combination of full-dose osimertinib and crizotinib in a patient with EGFR-mutant non-small cell lung cancer and emergent MET amplification
Zhu VW, Schrock AB, Ali SM, Ou SI
Lung Cancer: Targets and Therapy 2019, 10:21-26
Published Date: 12 March 2019
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Dramatic response to alectinib in a lung cancer patient with a novel VKORC1L1-ALK fusion and an acquired ALK T1151K mutation
Zhu VW, Schrock AB, Bosemani T, Benn BS, Ali SM, Ou SI
Lung Cancer: Targets and Therapy 2018, 9:111-116
Published Date: 8 November 2018
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Cis-oriented solvent-front EGFR G796S mutation in tissue and ctDNA in a patient progressing on osimertinib: a case report and review of the literature
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Klempner SJ, Mehta P, Schrock AB, Ali SM, Ou SI
Lung Cancer: Targets and Therapy 2017, 8:241-247
Published Date: 6 December 2017
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Dacomitinib in lung cancer: a “lost generation” EGFR tyrosine-kinase inhibitor from a bygone era?
Ou SH, Soo RA
Drug Design, Development and Therapy 2015, 9:5641-5653
Published Date: 15 October 2015
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Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged nonsmall cell lung cancer and beyond
Ou SH
Drug Design, Development and Therapy 2011, 5:471-485
Published Date: 23 November 2011