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Review

Noteworthy comment: Optimal management of CV risk factors, rate-rhythm, and sequellae in patients with AF is a major clinical concern. Components of relevant decision-making processes are cogently highlighted by the authors in this review. Recent novel anticoagulants provide additional choices in patients at high risk, but ultimately, barring contraindications, anticoagulation with either warfarin or a newer agent such as dabigatran, is recommended. Several issues remain open, pending future data. Outcomes are often not only limited by age and comorbidities, but also by significant non-ideal patient adherence.

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Management of patients with atrial fibrillation at high risk of stroke: current treatment options

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