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Drug Design, Development and Therapy
ISSN: 1177-8881
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Archive: Volume 18, 2024
- default (97)
- Advances in design and development of ophthalmic drugs (5)
- Beyond Brain Boundaries: Overcoming the Blood-Brain Barrier to Reach the Central Nervous System (1)
- Using Innovative Drug Delivery Systems to Improve the Efficacy and Applicability of Poorly Water-soluble Drugs (1)
Research Progress of Long Non-Coding RNA in Tumor Drug Resistance: A New Paradigm
Zhang J, Wu L, Wang C, Xie X, Han Y
Drug Design, Development and Therapy 2024, 18:1385-1398
Published Date: 26 April 2024
Dynasore Alleviates LPS-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis
Shan M, Wan H, Ran L, Ye J, Xie W, Lu J, Hu X, Deng S, Zhang W, Chen M, Wang F, Guo Z
Drug Design, Development and Therapy 2024, 18:1369-1384
Published Date: 23 April 2024
Propofol and Dexmedetomidine Ameliorate Endotoxemia-Associated Encephalopathy via Inhibiting Ferroptosis
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Drug Design, Development and Therapy 2024, 18:1349-1368
Published Date: 23 April 2024
Effect of Fluid Therapy in Early Morning on the Incidence of Post-Induction Hypotension During Non-Cardiac Surgery After Noon: A Single-Center Retrospective Study
Zhang Y, Wang X, Sang X, Zhou Z, Dai G, Zhang X
Drug Design, Development and Therapy 2024, 18:1339-1347
Published Date: 22 April 2024
Validation of Core Ingredients and Molecular Mechanism of Cinobufotalin Injection Against Liver Cancer
Chen S, Li M, Xue C, Zhou X, Wei J, Zheng L, Duan Y, Deng H, Tang F, Xiong W, Xiang B, Zhou M
Drug Design, Development and Therapy 2024, 18:1321-1338
Published Date: 23 April 2024
The Median Effective Dose of Intrathecal Hyperbaric Bupivacaine for Cesarean Section at Moderately High-Altitude
Yang C, Dong W, Luo J, Ma M, Gao Y, Ni L, Liu H, Cha C, Xiao Y, Huang S
Drug Design, Development and Therapy 2024, 18:1313-1319
Published Date: 22 April 2024
Natural and Synthetic Drugs Approached for the Treatment of Recurrent Aphthous Stomatitis Over the Last Decade
Vitamia C, Iftinan GN, Latarissa IR, Wilar G, Cahyanto A, Elamin KM, Wathoni N
Drug Design, Development and Therapy 2024, 18:1297-1312
Published Date: 22 April 2024
RNA-Based Antipsoriatic Gene Therapy: An Updated Review Focusing on Evidence from Animal Models
Lin ZC, Hung CF, Aljuffali IA, Lin MH, Fang JY
Drug Design, Development and Therapy 2024, 18:1277-1296
Published Date: 23 April 2024
Obacunone Alleviates Inflammatory Pain by Promoting M2 Microglial Polarization and by Activating Nrf2/HO-1 Signaling Pathway
Nan F, Tian Q, Chen S
Drug Design, Development and Therapy 2024, 18:1265-1275
Published Date: 18 April 2024
Cinnamaldehyde Inhibits the Function of Osteosarcoma by Suppressing the Wnt/β-Catenin and PI3K/Akt Signaling Pathways [Retraction]
Huang Y, Chen J, Yang S, Tan T, Wang N, Wang Y, Zhang L, Yang C, Huang H, Luo J, Luo X
Drug Design, Development and Therapy 2024, 18:1263-1264
Published Date: 18 April 2024
Sinomenine Hydrochloride Protects IgA Nephropathy Through Regulating Cell Growth and Apoptosis of T and B Lymphocytes
Li JJ, Li L, Li S, Tang XY, Sun HF, Liu JX
Drug Design, Development and Therapy 2024, 18:1247-1262
Published Date: 17 April 2024
Dexamethasone versus Dexmedetomidine as Adjuvants in Ultrasound Popliteal Sciatic Nerve Block for Hallux Valgus Surgery: A Mono-Centric Retrospective Comparative Study
Coviello A, Iacovazzo C, Cirillo D, Bernasconi A, Marra A, Squillacioti F, Martone M, Garone E, Coppola F, de Siena AU, Vargas M, Servillo G
Drug Design, Development and Therapy 2024, 18:1231-1245
Published Date: 17 April 2024
Clinical Application and Research Progress of Remimazolam for Pediatric Patients
Bai C, Xu M, Guo Y, Jin Y, Zhao X
Drug Design, Development and Therapy 2024, 18:1221-1229
Published Date: 17 April 2024
Network Pharmacology and Molecular Docking Identify the Potential Mechanism and Therapeutic Role of Scutellaria baicalensis in Alzheimer’s Disease
Peng Y, Zhou C
Drug Design, Development and Therapy 2024, 18:1199-1219
Published Date: 17 April 2024
Effect of S-Ketamine on Postoperative Nausea and Vomiting in Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trial
Qi Y, Zhou M, Zheng W, Dong Y, Li W, Wang L, Xu H, Zhang M, Yang D, Wang L, Zhou H
Drug Design, Development and Therapy 2024, 18:1189-1198
Published Date: 16 April 2024
A Novel Network Pharmacology Strategy Based on the Universal Effectiveness-Common Mechanism of Medical Herbs Uncovers Therapeutic Targets in Traumatic Brain Injury
Yu Z, Ding R, Yan Q, Cheng M, Li T, Zheng F, Zhu L, Wang Y, Tang T, Hu E
Drug Design, Development and Therapy 2024, 18:1175-1188
Published Date: 16 April 2024
Citric Acid Controls the Activity of YopH Bacterial Tyrosine Phosphatase
Styszko J, Kostrzewa T, Gorska-Ponikowska M, Kuban-Jankowska A
Drug Design, Development and Therapy 2024, 18:1165-1174
Published Date: 11 April 2024
Outcome of Darunavir–Cobicistat-Based Regimens in HIV-Infected People Who Have Experienced Virological Failure
Alberton F, Galli L, Lolatto R, Candela C, Gianotti N, Chiurlo M, Ranzenigo M, Strano M, Uglietti A, Castagna A
Drug Design, Development and Therapy 2024, 18:1153-1163
Published Date: 10 April 2024
The Promise of Therapeutic Psilocybin: An Evaluation of the 134 Clinical Trials, 54 Potential Indications, and 0 Marketing Approvals on ClinicalTrials.gov
Norring SA, Spigarelli MG
Drug Design, Development and Therapy 2024, 18:1143-1151
Published Date: 10 April 2024
Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats
Chayah M, Luque-González A, Gómez-Pérez V, Salagre D, Al-Shdaifat A, Campos JM, Conejo-García A, Agil A
Drug Design, Development and Therapy 2024, 18:1133-1141
Published Date: 10 April 2024
Unveiling the Mechanism of the ChaiShao Shugan Formula Against Triple-Negative Breast Cancer
Fan T, Huang Y, Liu Z, Huang J, Ke B, Rong Y, Qiu H, Zhang B
Drug Design, Development and Therapy 2024, 18:1115-1131
Published Date: 10 April 2024
Dexmedetomidine Prolongs Lidocaine Intravenous Regional Anesthesia in Rats by Blocking the Hyperpolarization-Activated Cation Current
Zhang T, Liao X, Chen Y, Shu X, Liu D, Yao Y
Drug Design, Development and Therapy 2024, 18:1103-1114
Published Date: 9 April 2024
Updated Evaluation of Agalsidase Alfa Enzyme Replacement Therapy for Patients with Fabry Disease: Insights from Real-World Data
Feriozzi S, Chimenti C, Reisin RC
Drug Design, Development and Therapy 2024, 18:1083-1101
Published Date: 3 April 2024
Mapping the Research of Ferroptosis in Parkinson’s Disease from 2013 to 2023: A Scientometric Review
Chen Y, Wu Z, Li S, Chen Q, Wang L, Qi X, Tian C, Yang M
Drug Design, Development and Therapy 2024, 18:1053-1081
Published Date: 3 April 2024
Molecular Modeling, Synthesis, and Antihyperglycemic Activity of the New Benzimidazole Derivatives – Imidazoline Receptor Agonists
Martynov A, Farber B, Bomko T, Beckles DL, Kleyn I
Drug Design, Development and Therapy 2024, 18:1035-1052
Published Date: 3 April 2024
Exploring the Median Effective Dose of Ciprofol for Anesthesia Induction in Elderly Patients: Impact of Frailty on ED50
Yuan J, Liang Z, Geoffrey MB, Xie Y, Chen S, Liu J, Xia Y, Li H, Zhao Y, Mao Y, Xing N, Yang J, Wang Z, Xing F
Drug Design, Development and Therapy 2024, 18:1025-1034
Published Date: 3 April 2024
Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling [LETTER]
Pasiana AD, Idrus HH, Purnamasari I
Drug Design, Development and Therapy 2024, 18:1023-1024
Published Date: 2 April 2024
The Emerging Roles of Nanocarrier Drug Delivery System in Treatment of Intervertebral Disc Degeneration-Current Knowledge, Hot Spots, Challenges and Future Perspectives
Hu Y, Yang R, Liu S, Song Z, Wang H
Drug Design, Development and Therapy 2024, 18:1007-1022
Published Date: 29 March 2024
Revolutionizing Stroke Recovery: Unveiling the Promise of Stem Cell Therapy
Panos LD, Bargiotas P, Arnold M, Hadjigeorgiou G, Panos GD
Drug Design, Development and Therapy 2024, 18:991-1006
Published Date: 29 March 2024
The Potential of Exosomes for Osteoporosis Treatment: A Review
He Y, Chen Y
Drug Design, Development and Therapy 2024, 18:979-989
Published Date: 28 March 2024
The Safety and Efficacy of Remimazolam Compared to Dexmedetomidine for Awake Tracheal Intubation by Flexible Bronchoscopy: A Randomized, Double-Blind, Controlled Trial
Chen Q, Qin B, Zhang M, Zhou Y, Shi X, Xie Y
Drug Design, Development and Therapy 2024, 18:967-978
Published Date: 28 March 2024
Neurophysiological Characteristics in Type II and Type III 5q Spinal Muscular Atrophy Patients: Impact of Nusinersen Treatment
Li D, Sun N, Xiang L, Liu J, Wang X, Yang L, Huang S
Drug Design, Development and Therapy 2024, 18:953-965
Published Date: 28 March 2024
A Review of Dupilumab in the Treatment of Atopic Dermatitis in Infants and Children
Wang M, Gao XH, Zhang L
Drug Design, Development and Therapy 2024, 18:941-951
Published Date: 27 March 2024
The Impact of Baohuoside I on the Metabolism of Tofacitinib in Rats
Shi Y, Lu Z, Song W, Wang Y, Zhou Q, Geng P, Zhou Y, Wang S, Han A
Drug Design, Development and Therapy 2024, 18:931-939
Published Date: 25 March 2024
Effect of Intraoperative infusion Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial
Xu H, Hao C, Wang X, Du J, Zhang T, Zhang X
Drug Design, Development and Therapy 2024, 18:919-929
Published Date: 25 March 2024
Intracranial Efficacy of Pyrotinib and Capecitabine Combination Therapy in HER2-Positive Breast Cancer with Brain Metastases
Wang C, Xiang J, Zhang Q, Li J, Liu Y, Liu J
Drug Design, Development and Therapy 2024, 18:909-917
Published Date: 23 March 2024
Harmonising IV Oxycodone with Paediatric Perioperative Medications: A Compatibility Study Through Y-Type Connectors
Youssef SH, Garg A, Song Y, Wylie NE, Garg S
Drug Design, Development and Therapy 2024, 18:899-908
Published Date: 22 March 2024
The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial
Wen T, Liu X, Pang T, Li M, Jiao G, Fan X, Tang J, Zhang C, Wang Z, Yue X, Chen W, Zhang F
Drug Design, Development and Therapy 2024, 18:881-897
Published Date: 21 March 2024
Optimal Once-Daily Busulfan Administration in Pediatric Patients: A Simulation-Based Investigation of Intravenous Infusion Times
Kim Y, Moon S, Rhee SJ
Drug Design, Development and Therapy 2024, 18:871-879
Published Date: 20 March 2024
A Novel DNA Aptamer Probe Recognizing Castration Resistant Prostate Cancer in vitro and in vivo Based on Cell-SELEX
Zhong J, Liu D, Yang Q, Ding J, Chen X
Drug Design, Development and Therapy 2024, 18:859-870
Published Date: 18 March 2024
Comparison of the Efficacy of Anti-Obesity Medications in Real-World Practice
Song JE, Ko HJ, Kim AS
Drug Design, Development and Therapy 2024, 18:845-858
Published Date: 18 March 2024
Understanding Sorafenib-Induced Cardiovascular Toxicity: Mechanisms and Treatment Implications
Li J, Zhang L, Ge T, Liu J, Wang C, Yu Q
Drug Design, Development and Therapy 2024, 18:829-843
Published Date: 18 March 2024
Development and Characterization of a Novel Carbon-11 Labeled Positron Emission Tomography Radiotracer for Neuroimaging of Sirtuin 1 with Benzoxazine-Based Compounds
Wang Y, Liu Y, Wang Y, Bai P, Hallisey MR, Varela BL, Siewko A, Wang C, Xu Y
Drug Design, Development and Therapy 2024, 18:819-827
Published Date: 15 March 2024
Model-Informed Precision Dosing of Isoniazid: Parametric Population Pharmacokinetics Model Repository
Ju G, Liu X, Yang W, Xu N, Chen L, Zhang C, He Q, Zhu X, Ouyang D
Drug Design, Development and Therapy 2024, 18:801-818
Published Date: 14 March 2024
Qifu Yixin Formula Improves Heart Failure by Enhancing β-Arrestin2 Mediated the SUMOylation of SERCA2a
Wang X, Yang J, Lu C, Hu Y, Xu Z, Wan Q, Zhang M, Shi T, Liu Z, Liu Y
Drug Design, Development and Therapy 2024, 18:781-799
Published Date: 11 March 2024
Forsythoside B Mitigates Monocrotaline-Induced Pulmonary Arterial Hypertension via Blocking the NF-κB Signaling Pathway to Attenuate Vascular Remodeling
Liu J, Fang G, Lan C, Qiu C, Yao L, Zhang Q, Hu J, Zhang Y, Yang Y, Zhang Y
Drug Design, Development and Therapy 2024, 18:767-780
Published Date: 11 March 2024
Mechanisms of Action of Potentilla discolor Bunge in Type 2 Diabetes Mellitus Based on Network Pharmacology and Experimental Verification in Drosophila
Li Y, Wu F, Zhang J, Xu Y, Chang H, Yu Y, Jiang C, Gao X, Liu H, Chen Z, Wu C, Li JA
Drug Design, Development and Therapy 2024, 18:747-766
Published Date: 11 March 2024
Bibliometric and Visualization Analysis of Stem Cell Therapy for Erectile Dysfunction
Sun T, Liu Y, Yuan P, Jia Z, Yang J
Drug Design, Development and Therapy 2024, 18:731-746
Published Date: 8 March 2024
UHPLC-qTOF-MS-Based Nontargeted Metabolomics to Characterize the Effects of Capsaicin on Plasma and Skin Metabolic Profiles of C57BL/6 Mice-An In vivo Experimental Study
Xiao Z, Yu S, Zhang D, Li C
Drug Design, Development and Therapy 2024, 18:719-729
Published Date: 5 March 2024
Integrated Network Pharmacology and in vivo Experimental Validation Approach to Explore the Potential Antioxidant Effects of Annao Pingchong Decoction in Intracerebral Hemorrhage Rats
Zhou X, Wang X, Li J, Zhang M, Yang Y, Lei S, He Y, Yang H, Zhou D, Guo C
Drug Design, Development and Therapy 2024, 18:699-717
Published Date: 4 March 2024
Penehyclidine for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Gynecological Laparoscopic Surgery Under Combined Intravenous and Inhalation Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial
Zhao K, Gao Y, Zhang J, Wang S, Chen J, Guo F, Wang S
Drug Design, Development and Therapy 2024, 18:685-697
Published Date: 1 March 2024
Safety and Effectiveness of a Biosimilar Recombinant Human Growth Hormone in Children Requiring Growth Hormone Treatment: Analysis of Final Data from PATRO Children, an International, Post-Marketing Surveillance Study
Loche S, Kanumakala S, Backeljauw P, Schwab KO, Lechuga-Sancho AM, Esmael A, Urosevic D, Boldea A, Zabransky M
Drug Design, Development and Therapy 2024, 18:667-684
Published Date: 2 March 2024
Exploration of the in vitro Antiviral Effects and the Active Components of Changyanning Tablets Against Enterovirus 71
Ge Q, Zhang Z, Cao Z, Wu D, Xu C, Yao J, Gao J, Feng Y
Drug Design, Development and Therapy 2024, 18:651-665
Published Date: 2 March 2024
Randomized Double-Blinded Comparison of Intermittent Boluses Phenylephrine and Norepinephrine for the Treatment of Postspinal Hypotension in Patients with Severe Pre-Eclampsia During Cesarean Section
Pan ZB, Sheng ZM, Zhu M, Mei Z, Shen YP, Liu JP, Qian XW
Drug Design, Development and Therapy 2024, 18:639-650
Published Date: 29 February 2024
Clinical Study of Flumazenil Antagonizing Remimazolam on Nausea and Vomiting After Gynecologic Day Surgery
Wei Y, Zhu M, Man Y, Xiao H, Dong G, Shi X, Ji F
Drug Design, Development and Therapy 2024, 18:631-638
Published Date: 4 March 2024
A Window for Enhanced Oral Delivery of Therapeutics via Lipid Nanoparticles
Amekyeh H, Sabra R, Billa N
Drug Design, Development and Therapy 2024, 18:613-630
Published Date: 29 February 2024
Synthesis of a New Series of Anthraquinone-Linked Cyclopentanone Derivatives: Investigating the Antioxidant, Antibacterial, Cytotoxic and Tyrosinase Inhibitory Activities of the Mushroom Tyrosinase Enzyme Using Molecular Docking
Mullaivendhan J, Akbar I, Ahamed A, Gatasheh MK, Hatamleh AA, Raman G, Manilal A, Kuzhunellil Raghavanpillai S
Drug Design, Development and Therapy 2024, 18:597-612
Published Date: 27 February 2024
Effects of Remifentanil Gradual Withdrawal Combined with Postoperative Infusion on Postoperative Hyperalgesia in Patients Undergoing Laparoscopic hysterectomy: A Factorial Design, Double-Blind, Randomized Controlled Trial
Luo M, Han X, Li H, Zhou G, Chen H, Gao F
Drug Design, Development and Therapy 2024, 18:583-595
Published Date: 27 February 2024
Pharmacokinetics, Pharmacodynamics, and Safety of Evocalcet (KHK7580), a Novel Calcimimetic Agent: An Open-Label, Single- and Multiple-Dose, Phase I Trial in Healthy Chinese Subjects
He X, Narushima K, Kojima M, Nagai C, Li K
Drug Design, Development and Therapy 2024, 18:567-581
Published Date: 26 February 2024
Protective Effects of Red Ginseng Against Tacrine-Induced Hepatotoxicity: An Integrated Approach with Network Pharmacology and Experimental Validation
Kim BJ, Bak SB, Bae SJ, Jin HJ, Park SM, Kim YR, Jung DH, Song CH, Kim YW, Kim SC, Lee WY, Park SD
Drug Design, Development and Therapy 2024, 18:549-566
Published Date: 23 February 2024
The Effects of Different Doses of Sufentanil on Intraoperative Cardiovascular Response and Postoperative Recovery in Patients Undergoing Cardiac Surgery: A Retrospective Cohort Study
Li M, Li X, Wu Y, Zhang T, Li M, Chen Y
Drug Design, Development and Therapy 2024, 18:535-547
Published Date: 23 February 2024
Immunomodulatory Role of Plants and Their Constituents on the Management of Metabolic Disorders: An Evidence-Based Review
Febriyanti RM, Levita J, Diantini A
Drug Design, Development and Therapy 2024, 18:513-534
Published Date: 23 February 2024
Network Pharmacology with Metabolomics Study to Reveal the Mechanisms of Bushen Huoxue Formula in Intervertebral Disc Degeneration Treatment
Guo J, Yang S, Zhai W, Xie Y, Shen Z, Zhang J, Jia Y
Drug Design, Development and Therapy 2024, 18:493-512
Published Date: 21 February 2024
Hydroxy-Safflower Yellow A Mitigates Vascular Remodeling in Rat Pulmonary Arterial Hypertension
Ji XY, Lei CJ, Kong S, Li HF, Pan SY, Chen YJ, Zhao FR, Zhu TT
Drug Design, Development and Therapy 2024, 18:475-491
Published Date: 20 February 2024
Efficacy of Intravenous Administration of Esketamine in Preventing and Treating Rebound Pain After Thoracic Paravertebral Nerve Block: A Prospective Randomized, Double-Blind, Placebo-Controlled Trial
Zeng X, Zhang X, Jiang W, Zhou X
Drug Design, Development and Therapy 2024, 18:463-473
Published Date: 17 February 2024
The Protective Effect of Roflumilast Against Acute Hepatotoxicity Caused by Methotrexate in Wistar Rats: In vivo Evaluation
Almalki RS
Drug Design, Development and Therapy 2024, 18:453-462
Published Date: 15 February 2024
Beneficial Effects of Low-Dose Intravenous Dexmedetomidine Premedication in Patient Undergoing Laparoscopic Cholecystectomy Under General Anesthesia: A Prospective, Double-Blind, Randomized Controlled Trial
Zheng L, Fang T, Zhang W, Zhang X, Ren Z, Qin W, Liang W, Ma Q, Yin N
Drug Design, Development and Therapy 2024, 18:443-452
Published Date: 13 February 2024
Molecular Mechanism of Salvia miltiorrhiza in the Treatment of Colorectal Cancer Based on Network Pharmacology and Molecular Docking Technology
Jiang YL, Xun Y
Drug Design, Development and Therapy 2024, 18:425-441
Published Date: 12 February 2024
Zishen Yutai Pills Promote Angiogenesis at the Maternal-Fetal Interface in Recurrent Spontaneous Abortion Mice by Regulating miR-187/VEGF Axis
Wang X, Hu H, Yu X, Liang C, Han Y, Chen H, Chu J
Drug Design, Development and Therapy 2024, 18:407-423
Published Date: 12 February 2024
Pharmacokinetic Comparison Between a Fixed-Dose Combination of Atorvastatin/Omega-3-Acid Ethyl Esters and the Corresponding Loose Combination in Healthy Korean Male Subjects
Khwarg J, Lee S, Jang IJ, Kang WH, Lee HJ, Kim KY, Jeong KS, Won C, Choi YW, Ha DC, Jung R, Han MG, Jung WT, Nam KY, Kim YS, Yu KS, Oh J
Drug Design, Development and Therapy 2024, 18:395-406
Published Date: 8 February 2024
A Comprehensive Study to Investigate the Tumor-Suppressive Role of Radix Bupleuri on Gastric Cancer with Network Pharmacology and Molecular Docking
Lv L, Du J, Wang D, Yan Z
Drug Design, Development and Therapy 2024, 18:375-394
Published Date: 8 February 2024
Ranibizumab Biosimilars in Treating Retinal Disorders: A Cost-Effective Revolution?
Chatzimichail E, Pfau K, Gatzioufas Z, Panos GD
Drug Design, Development and Therapy 2024, 18:365-374
Published Date: 8 February 2024
Comparative Study Between Dexmedetomidine with Bupivacaine and Bupivacaine Alone in Erector Spinae Plane Block for Postoperative Pain Control of Posterior Lumbosacral Spine Fixation Surgeries: A Randomized Controlled Trial
Abu El Hassan SH, Wahsh EA, Mousa AM, Ibrahim ARN, Mohammed EL
Drug Design, Development and Therapy 2024, 18:351-363
Published Date: 7 February 2024
Remifentanil is Superior to Propofol for Treating Emergence Agitation in Adults After General Anesthesia
Li J, Zhu H, Wang Y, Chen J, He K, Wang S
Drug Design, Development and Therapy 2024, 18:341-350
Published Date: 7 February 2024
The Effect of Ciprofol on Postoperative Delirium in Elderly Patients Undergoing Thoracoscopic Surgery for Lung Cancer: A Prospective, Randomized, Controlled Trial
Liu Z, Jin Y, Wang L, Huang Z
Drug Design, Development and Therapy 2024, 18:325-339
Published Date: 5 February 2024
The Potential Application of Aloe Barbadensis Mill. as Chinese Medicine for Constipation: Mini-Review
Huang WR, Fang QH, Yu XB, Ge WH, Yu Y
Drug Design, Development and Therapy 2024, 18:307-324
Published Date: 3 February 2024
Developments in the Management of Growth Hormone Deficiency: Clinical Utility of Somapacitan
Miller BS, Blair J, Horikawa R, Linglart A, Yuen KC
Drug Design, Development and Therapy 2024, 18:291-306
Published Date: 3 February 2024
Dupilumab Treatment in Pediatric Patients Aged 6–11 Years with Severe Atopic Dermatitis Whose Disease Is Not Adequately Controlled: A Review
Cork MJ, Danby SG, Rossi AB, Bansal A
Drug Design, Development and Therapy 2024, 18:277-289
Published Date: 3 February 2024
Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis
Chen K, Yu Y, Wang Y, Zhu Y, Qin C, Xu J, Zou X, Tao T, Li Y, Jiang Y
Drug Design, Development and Therapy 2024, 18:259-275
Published Date: 1 February 2024
Berberine Nanoparticles with Enhanced in vitro Bioavailability: Characterization and Antimicrobial Activity [Retraction]
Sahibzada MUK, Sadiq A, Faidah HS, Khurram M, Amin MU, Haseeb A, Kakar M
Drug Design, Development and Therapy 2024, 18:257-258
Published Date: 2 February 2024
Guidelines for Rational Clinical Use of Fentanyl Transdermal Patch
Fu Q, Han N, Li N, Gui L, Shi C, Rong P, Zeng F, Rao H, Chen Y
Drug Design, Development and Therapy 2024, 18:233-255
Published Date: 1 February 2024
Effect of Perioperative Nicorandil on Myocardial Protection in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass, a Retrospective Study
Chen Y, Liu Y, Lv H, Li Q, Shen J, Chen W, Shi J, Zhou C
Drug Design, Development and Therapy 2024, 18:223-231
Published Date: 31 January 2024
Synthesis and Characterization of a New Carbon-11 Labeled Positron Emission Tomography Radiotracer for Orexin 2 Receptors Neuroimaging
Wang Y, Wang Y, Liu Y, Cheng H, Dagnew TM, Xu Y, Wang C
Drug Design, Development and Therapy 2024, 18:215-222
Published Date: 31 January 2024
Plants with Anti-Ulcer Activity and Mechanism: A Review of Preclinical and Clinical Studies
Prayoga DK, Aulifa DL, Budiman A, Levita J
Drug Design, Development and Therapy 2024, 18:193-213
Published Date: 1 February 2024
Review of the Protective Mechanism of Curcumin on Cardiovascular Disease
Yang C, Zhu Q, Chen Y, Ji K, Li S, Wu Q, Pan Q, Li J
Drug Design, Development and Therapy 2024, 18:165-192
Published Date: 30 January 2024
Interactive Nutrient Process (INP) in a Generative AI of a New Drug—6-Shogaol as a Potential Case
Badmaev V
Drug Design, Development and Therapy 2024, 18:161-163
Published Date: 27 January 2024
In vitro and in vivo Biological Evaluation of Newly Tacrine-Selegiline Hybrids as Multi-Target Inhibitors of Cholinesterases and Monoamine Oxidases for Alzheimer’s Disease
Huang ST, Luo JC, Zhong GH, Teng LP, Yang CY, Tang CL, Jing L, Zhou ZB, Liu J, Jiang N
Drug Design, Development and Therapy 2024, 18:133-159
Published Date: 24 January 2024
Comparison of Remimazolam versus Sevoflurane on the Postoperative Quality of Recovery in Cervical Spine Surgery: A Prospective Randomized Controlled Double-Blind Trial
Lee J, Han DW, Kim NY, Kim KS, Yang Y, Yang J, Lee HS, Kim MH
Drug Design, Development and Therapy 2024, 18:121-132
Published Date: 23 January 2024
The Effect of Platelet Activity, ABCB1 Genetic Polymorphism, and Renal Function on the Development of Ticagrelor-Related Dyspnea in Patients with Acute Coronary Syndrome
Tamakauskas V, Žaliūnas R, Lesauskaitė V, Kupstytė-Krištaponė N, Čiapienė I, Šakalytė G, Plisienė J, Skipskis V, Tatarūnas V
Drug Design, Development and Therapy 2024, 18:109-119
Published Date: 23 January 2024
The Role of Rho Kinase Inhibitors in Corneal Diseases
Futterknecht S, Chatzimichail E, Gugleta K, Panos GD, Gatzioufas Z
Drug Design, Development and Therapy 2024, 18:97-108
Published Date: 19 January 2024
Population Pharmacokinetics and Model-Based Dose Optimization of Vancomycin in Sudanese Adult Patients with Renal Impairment
Ahmed KA, Ibrahim A, Gonzalez D, Nur AO
Drug Design, Development and Therapy 2024, 18:81-95
Published Date: 16 January 2024
Nicotine Diminishes Alpha2-Adrenergic Receptor-Dependent Protection Against Oxidative Stress in H9c2 Cardiomyocytes
Del Calvo G, Pollard CM, Baggio Lopez T, Borges JI, Suster MS, Lymperopoulos A
Drug Design, Development and Therapy 2024, 18:71-80
Published Date: 12 January 2024
Immunosuppression with Generics in Liver and Kidney Transplantation: A Real-World Evidence Study
Finocchietti M, Marino ML, Rosa AC, Bellini A, Masiero L, Cardillo M, Massari M, Spila Alegiani S, Pierobon S, Ferroni E, Zanforlini M, Leoni O, Ledda S, Garau D, Davoli M, Addis A, Belleudi V
Drug Design, Development and Therapy 2024, 18:53-69
Published Date: 12 January 2024
Effect of High-Fat Meal on the Pharmacokinetics and Safety of Valsartan/Amlodipine Fixed Dose Combination Tablets in Healthy Subjects
Song H, Qiu B, Sun X, Guo C, Hu Y, Bai W, Dong Z
Drug Design, Development and Therapy 2024, 18:43-51
Published Date: 11 January 2024
Synthesis and Application of a Near-Infrared Light-Emitting Fluorescent Probe for Specific Imaging of Cancer Cells with High Sensitivity and Selectivity
Li S, Lin Z, Chen H, Luo Q, Han S, Huang K, Chen R, Zhan Y, Chen B, Yao H
Drug Design, Development and Therapy 2024, 18:29-41
Published Date: 10 January 2024
Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment
Zhao J, Zhao C, Xun T, Wang X, Wei S, Ye C, Zhang M, Guo D, Yang X
Drug Design, Development and Therapy 2024, 18:13-28
Published Date: 6 January 2024
Pharmacokinetics, Bioavailability, and Tissue Distribution of the Kirsten Rat Sarcoma Inhibitor Adagrasib in Rats Using UPLC-MS/MS
Lei P, Shen W, Tang H, You L, Chen G, Tang Y, Lu W
Drug Design, Development and Therapy 2024, 18:1-12
Published Date: 5 January 2024